Deep TMS for depression and memory problems in older adults
Part of Brain & nervous system, Mental health clinical trials.
This study tests a type of brain stimulation called Deep TMS to help reduce depression and improve or stabilize memory-related symptoms in older adults with Alzheimer’s disease. It’s mainly for people whose depression did not improve or could not be tolerated with antidepressant medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Alzheimer’s-related memory problems and a dementia rating score of 0.5 or higher
- You also have major depression or mild depression that has lasted more than 4 weeks but less than 5 years
- Your depression has not improved with antidepressants or you couldn’t tolerate them
- You can keep your medication routine steady for about 2 months before starting, and you won’t be expected to change meds during the study
- You’re able to complete the TMS sessions on the study schedule and pass the TMS safety checks
- You have a study partner (informant) who can help fill out questionnaires
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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