Ultrasound treatment to open the brain barrier for Alzheimer’s
Part of Brain & nervous system, Mental health clinical trials.
This trial tests a non-surgical ultrasound procedure (called MR-guided focused ultrasound) meant to temporarily “open” the brain’s protective barrier so treatments may work better for Alzheimer’s disease. It also looks at safety and how well people tolerate the procedure and related tests.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 85 years old.
- You have “probable” Alzheimer’s disease, as diagnosed by your doctor.
- If you take Alzheimer’s medicines, you’ve been on a stable dose for at least 3 months (and overall at least 2 months).
- You can speak up and describe what you feel during the ultrasound procedure.
- You can walk or move around on your own (ambulatory).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new treatment using focused ultrasound to temporarily open the barrier between your blood and brain. This may allow natural waste-clearing cells to work better and help slow the progression of Alzheimer's symptoms.
This study tests whether gentle, low-intensity ultrasound waves focused on certain brain areas can help people with early memory loss from Alzheimer's disease. It is a non-invasive treatment that might improve brain function without surgery.
This early study (Phase 1/2) uses brain imaging to look for “fibrin” (a blood-clot–related protein) in people with Alzheimer’s disease and related conditions. The goal is to understand whether fibrin changes can be seen on scans and what it might mean for Alzheimer’s.
This trial tests a new stem cell treatment (called RB-ADSCs) that is injected into the fluid around your brain. It aims to see if these cells can help slow down memory loss and thinking problems in people with mild to moderate Alzheimer's disease.
This trial tests whether a targeted deep brain stimulation treatment can help people with early Alzheimer’s disease symptoms and memory loss. It also involves brain imaging and a surgery/anesthesia procedure to place the stimulator.
This trial tests whether a focused ultrasound treatment can safely open the blood-brain barrier in people with Alzheimer's or mild cognitive impairment. The goal is to see if this helps clear amyloid and tau proteins from the brain, which might slow down memory loss.
Hear when a new Alzheimer Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.