Brain stimulation and neck surgery for severe Alzheimer's
Part of Brain & nervous system, Mental health clinical trials.
This early-stage trial tests combining deep brain stimulation (a device that sends electrical pulses to the brain) with a neck surgery that aims to improve brain fluid drainage. It's for people with severe Alzheimer's who can still walk and do not have other major health issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with Alzheimer's disease by a doctor
- Have severe dementia (CDR score of 3)
- Can walk on your own or with a walker/cane
- Never had brain surgery, no metal implants (like a pacemaker), and no other serious brain conditions
- No other major health problems or addictions that would make the trial unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new surgery called cervical lymphatic bypass to see if it can help people with Alzheimer's disease. The surgery creates a new connection in the neck to improve drainage of waste from the brain, which may slow memory loss.
This trial tests whether deep brain stimulation of a specific brain area can help people with Alzheimer's disease. It aims to see if this treatment can improve symptoms and quality of life.
This trial tests a surgical procedure (deep cervical lymphaticovenous anastomosis) for people with moderate-to-severe dementia. The goal is to see if the surgery can improve symptoms by helping the brain's drainage system.
This trial tests a new surgery on neck lymph vessels to see if it helps people with Alzheimer's. It is for patients aged 60 to 80 with mild to severe Alzheimer's who have had the diagnosis for over a year.
This trial tests whether a targeted deep brain stimulation treatment can help people with early Alzheimer’s disease symptoms and memory loss. It also involves brain imaging and a surgery/anesthesia procedure to place the stimulator.
This study tests a surgical procedure to connect lymph vessels in the neck to veins, which may help clear waste from the brain in people with mild cognitive impairment or mild to moderate Alzheimer's disease. It is for patients who have not improved after at least 3 months of standard care.
Hear when a new Alzheimer Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.