Mesenchymal stem cell treatment for lupus kidney inflammation
Treatments studied
Part of Immune system & allergy, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.
This trial tests whether donated (allogeneic) stem cells can improve lupus nephritis, a kidney complication of lupus. It is for adults whose lupus kidney disease has not responded well to standard treatments or has come back, and it requires signs of active disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 or older and able to give written consent
- Have lupus (SLE) confirmed by standard diagnostic criteria
- Have lupus nephritis proven by a recent kidney biopsy (within 6 months for new entry, or within 1 year for a recurrence)
- Have active lupus kidney disease that is not responding, or has returned, with SLE disease activity score (SLEDAI-2K) of 10 or higher
- Have had pneumococcal and flu vaccines during the study’s vaccine campaign
- Agree to prevent pregnancy if you could become pregnant (use reliable birth control)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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