Testing two breathing machines in very preterm babies
Part of Lungs & breathing, Women’s health & pregnancy clinical trials.
This study compares two ways of helping very preterm infants breathe: a special high-frequency ventilation method versus the standard mechanical ventilator. It aims to see which method works better for preterm babies with breathing failure soon after birth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Baby was born very early, between 24 weeks 0 days and 31 weeks 6 days.
- Baby went to the NICU within 1 hour after birth.
- Baby was diagnosed with breathing distress caused by the birth event (perinatal ARDS) and was on a ventilator.
- Before randomization, baby must be “stable on the ventilator” for 2 hours, with specific blood oxygen, breathing rate, and blood gas values.
- Parents/guardians must agree to join the study.
- Baby must not have major birth defects, major chromosome problems, or serious brain bleeding before the study starts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new breathing method (high-frequency oscillatory ventilation) for patients in the ICU who need a breathing tube. It looks at how safe it is and how it affects the body, and is for people with certain lung problems like ARDS or collapsed lungs.
This study tests whether delivering breathing support through a soft face mask (nasal non-invasive ventilation) can help premature babies who are having trouble breathing. Doctors will also use ultrasound to monitor their lungs.
This trial tests two different ways to safely take preterm babies off a special breathing machine (HFOV). It aims to find which method works better for babies with breathing problems (respiratory distress syndrome).
This study tests a new way of using a breathing machine (high-frequency ventilation) for premature babies with breathing problems. It may help your baby's lungs work better if they were born early and need help breathing.
This trial is studying how to use a special breathing machine (high frequency oscillatory ventilation) in newborns. The goal is to improve the settings for better breathing support.
This study tests how different nasal high-flow “flow strength” settings affect breathing stability in preterm infants. It may help clinicians choose settings that keep heart rate and breathing steadier.
Hear when a new Acute Respiratory Distress Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.