Clin2
NCT03826524Likely a fitRecruiting

Comparing two doses of epinephrine for cardiac arrest

Cardiac Arrest, Out-Of-HospitalSudden Cardiac ArrestVentricular FibrillationVentricular Tachycardia-Pulseless

Treatments studied

Part of Heart & circulation clinical trials.

This study looks at whether a higher dose of epinephrine (a medicine that helps restart the heart) is better than the standard dose for people whose heart has stopped outside of a hospital. It aims to see if one dose leads to better survival and recovery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
1,250 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older
  • Your heart stopped while outside of a hospital and emergency responders treated you
  • The first heart rhythm was one that can be helped by an electric shock (shockable rhythm)
  • Emergency responders were able to start an IV line (a small tube in a vein) to give medicines

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07596446Recruiting
Emergency treatment study for cardiac arrest patients

This study tests emergency treatments for people who have had a cardiac arrest (heart stops beating) outside the hospital. It looks at two groups: people whose hearts stop despite CPR efforts, and people whose hearts have restarted. The goal is to see if these treatments can help patients survive and recover better.

Prague
NCT07041086Recruiting
Prehospital ECMO for cardiac arrest

This trial tests whether giving ECMO (a heart-lung machine) to people in cardiac arrest before they reach the hospital can improve survival. It might be an option if you had a witnessed heart attack and received CPR quickly.

Ostrava, Moravian-Silesian Region
NCT06603649Not yet recruiting
Updated care for persistent cardiac arrest outside hospital

This study tests a new way of managing adults whose hearts stop outside a hospital and who haven't responded to usual CPR. It aims to see if the updated procedure improves survival and recovery.

Nancy
NCT05969028Recruiting
Testing breathing and chest compression timing for out-of-hospital cardiac arrest

This trial studies the best timing for chest compressions and airway management for adults who have sudden cardiac arrest outside the hospital. It may help improve survival chances by guiding first EMS responders on how to act sooner and more consistently.

Seattle, Washington
NCT07442071Not yet recruiting· Phase 3
Low-dose epinephrine to improve brain recovery after cardiac arrest outside the hospital

This study tests whether giving a low dose of epinephrine (a medicine that helps restart the heart) during a cardiac arrest can improve brain recovery. It compares standard treatment with adding this low dose to see if more patients recover without brain damage.

Annecy
NCT06473116Not yet recruiting· Phase 4
Epinephrine vs isoprenaline for cardiac arrest with no heartbeat

This trial compares two medications, epinephrine and isoprenaline, given to people who have a cardiac arrest (heart stops beating) with a specific heart rhythm called asystole (flatline). The goal is to see which drug is better at restarting the heart and improving chances of survival.

Odense

Hear when a new Sudden Cardiac Arrest trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.