Cell graft for severe damage to both eyes’ surface
Part of Eyes & vision clinical trials.
This Phase 1/2 trial tests a treatment made from your own mouth tissue cells to help regrow the front surface of the eye when both eyes have severe limbal stem cell deficiency. If you qualify, you may receive an autologous (made from your own tissue) cell sheet to improve eye healing and vision.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You can sign informed consent
- Both eyes have severe limbal stem-cell deficiency caused by injury, transplant, or another bilateral problem
- Your vision is very reduced (less than 2/10 or similar score)
- You are covered by a social security system
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests transplanting your own limbal and corneal stromal stem cells to repair corneal damage from a chemical burn. It may help if standard treatments have not improved your eye surface.
This trial studies a type of eye surface transplant to help when the eye’s limbal “stem cells” are missing or not working well. If you have severe limbal stem cell deficiency in one or both eyes, this treatment may help the eye heal and stay healthier.
This trial tests an eye treatment made from your own cornea surface cells, grown in a lab and put back into the eye. It may help people with limbal stem cell deficiency by improving the health of the eye surface after a cell biopsy.
This Phase 2 trial tests a locally delivered cell-based treatment (allogeneic mesenchymal stromal cells) to help heal long-lasting damage to the eye’s clear surface (the cornea). It may help if your cornea epithelium (surface layer) won’t improve even after standard non-surgical treatments.
This study is testing a new way to use a small piece of your cheek tissue to repair the surface of your eye. It may help people with certain eye conditions, like recurring growths, tumors, or burns.
This trial tests whether eye drops made from your own blood (called autologous serum) can help heal dry eye or damage on the surface of your eye. If you have severe dry eye or a sore that won't heal on your eye's outer layer, you may be able to join.
Hear when a new Total Bilateral Limbal Cell Deficiency trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.