Mouth cell transplant for severe eye surface damage
Part of Eyes & vision, Immune system & allergy, Injuries & trauma, Mouth & dental, Skin clinical trials.
This trial tests a new way to repair the eye surface by using a thin sheet of cells from your own mouth, which are grown in the lab and then placed on your eye. It may help people whose eye damage hasn't improved with other treatments and who have very poor vision.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a damaged eye surface from limbal stem cell deficiency, and the cornea has developed a cloudy covering.
- Past treatments like a limbal transplant or amniotic membrane transplant haven't worked, or you can't take long-term immune-suppressing drugs.
- Your vision in the affected eye is very poor—worse than counting fingers.
- You are at least 16 years old.
- You are not pregnant or planning pregnancy within a year, and you don't have active infections, serious heart or brain disease, cancer, or a cow protein allergy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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