Botulinum toxin to block a facial nerve for chronic cluster headaches
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests whether injections of botulinum toxin type A can reduce frequent, severe cluster headache attacks by targeting a facial nerve area. It’s for people whose cluster headaches have not responded well—or have caused side effects—to standard preventive treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 85 years old and can sign consent forms
- You have chronic cluster headache, with at least 4 attacks per week for the last 3 months
- Most of your attacks (at least 80%) happen on the same side of your head
- Your headaches did not respond well to verapamil or lithium, or you can’t take them, or you couldn’t tolerate them
- You can tell the difference between cluster headaches and other headache types
- You will keep your current preventive headache medicines the same dose and schedule during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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