Treatment
Tenecteplase clinical trials
We’re tracking 40 recruiting studies that include Tenecteplase, each written for real people, not researchers, below.
Recruiting studies
- NCT07294209RecruitingPhase 4
Low-dose tenecteplase for older adults with stroke
This trial tests a lower dose of the clot-busting drug tenecteplase in people aged 70 and older who have had an ischemic stroke. It aims to see if this treatment is safe and effective for older patients when given within 4.5 hours of symptoms starting.
Chongqing, Chongqing MunicipalityAges 70 years+ - NCT06352632RecruitingPhase 3
Adaptive Stroke Trial Testing New Treatments
This trial is testing different treatments for stroke patients to find which work best. It's designed to adapt over time so new treatments can be added as research progresses.
Sydney, New South WalesAges 18 years+ - NCT06621121Recruiting
Comparing two clot-busting drugs for stroke within 4.5 hours
This study compares two medications, tenecteplase and alteplase, to see which works better at dissolving blood clots in people having an ischemic stroke. You may join if you can get treatment within 4.5 hours of when your symptoms started.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07357987RecruitingPhase 3
Stroke treatment with tenecteplase via artery
This trial tests a clot-busting drug called tenecteplase given directly into the brain artery for people having a moderate stroke caused by a blockage in a medium-sized blood vessel. The goal is to see if it helps improve recovery when given within 24 hours of stroke symptoms starting.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07361302RecruitingPhase 3
Tenecteplase for stroke after 4.5 hours
This trial tests a clot-dissolving medicine called tenecteplase for people who had a stroke more than 4.5 hours ago. It may help you recover if given later than usual.
Buenos AiresAges 18 years+ - NCT07253181RecruitingPhase 3
Stroke clot-busting drug before transfer for artery clearing
This trial tests whether giving a clot-busting drug (tenecteplase) before transferring you to a hospital that can do a procedure to remove the clot improves outcomes for people who had a stroke up to 24 hours earlier. You may qualify if you have a blockage in a large artery in the front of your brain and can still get the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06904911RecruitingPhase 2
Study of tenecteplase into the artery after clot removal for stroke
This study tests a clot-dissolving drug called tenecteplase given directly into the artery after a mechanical thrombectomy (clot removal). The goal is to see if it helps improve blood flow to the small vessels in the brain after the main clot is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06868511RecruitingPhase 3
Minimally invasive clot removal with tenecteplase for deep brain bleed
This trial tests a minimally invasive procedure to remove deep brain bleeds using a special puncture guided by brain imaging, combined with a clot-dissolving drug called tenecteplase. It may help reduce damage from the bleed and improve recovery.
Beijing, ChinaAges 18–80 - NCT05105633RecruitingPhase 2/Phase 3
Tenecteplase for basilar stroke within an extended time window
This trial tests whether giving a clot-busting medicine (tenecteplase) can help people with a specific type of stroke caused by a basilar artery blockage, even if treatment starts later than usual. It aims to improve brain recovery and function by reopening the blocked artery.
Bankstown, New South WalesAges 18 years+ - NCT05199194RecruitingPhase 3
Clot-busting before or during procedure for acute stroke
This study compares two treatment approaches for a stroke caused by a blocked brain artery: doing a procedure to remove the clot alone versus giving an IV clot-busting medicine first (tenecteplase). It aims to see which approach works better and is safest for improving recovery.
Porto Alegre, Rio Grande do SulAges 18–85 - NCT05892510RecruitingPhase 2/Phase 3
Tenecteplase after clot removal for no-reflow stroke
This trial tests whether giving tenecteplase directly into the brain artery after a thrombectomy can improve outcomes when blood flow doesn’t fully return (“no-reflow”) in an emergency stroke. It may help some people by reducing ongoing clot-related blockage after the main clot is removed.
Gold Coast, QueenslandAges 18 years+ - NCT06010628RecruitingPhase 4
Tenecteplase for stroke 4.5 to 6 hours after onset
This trial tests a medicine called tenecteplase (a clot-buster) for people who have a moderate or severe stroke caused by a clot and can be treated 4.5 to 6 hours after symptoms start. It aims to see if this medicine can help improve recovery.
Shenyang, None SelectedAges 18 years+ - NCT06658197RecruitingPhase 3
Comparing a new clot-busting drug for severe stroke
This study tests a medication called tenecteplase, given before a procedure to remove a large blood clot in the brain. It may help people who have had a severe stroke within the last 4.5 hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06949228RecruitingPhase 2/Phase 3
Intra-Arterial Tenecteplase After Clot Removal for Stroke
This trial tests whether giving a clot-busting drug called tenecteplase directly into the brain artery after a successful mechanical clot removal can improve recovery for people with a certain type of stroke. The goal is to see if it safely helps clear any remaining tiny clots and reduces disability.
Toledo, OhioAges 18–85 - NCT06954155RecruitingPhase 3
Tenecteplase for stroke treatment 24-72 hours after symptoms start
This trial tests if the clot-busting drug tenecteplase can help people with a moderate to severe stroke when given 24 to 72 hours after symptoms began. It aims to see if this later treatment window can improve recovery and reduce disability.
BeijingAges 18 years+ - NCT07047014RecruitingPhase 3
Tenecteplase for medium vessel occlusion stroke (ARTS trial)
This trial tests the clot-busting drug tenecteplase in people who had a stroke 4.5 to 24 hours ago due to a medium-sized artery blockage. It aims to see if this medication can improve outcomes without needing a procedure to remove the clot.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07092709RecruitingPhase 3
Tenecteplase for stroke patients who recently took blood thinners
This trial tests if the clot-busting drug tenecteplase is safe and effective for people having an ischemic stroke who have recently taken blood thinners (DOACs). If you qualify, you may receive either tenecteplase or a placebo within 24 hours of your last known well time.
Guangzhou, GuangdongAges 18 years+ - NCT07203625RecruitingPhase 4
Tenecteplase before transfer for basilar artery stroke
This trial tests if a clot-busting drug called Tenecteplase helps people with a severe type of stroke in the back of the brain (basilar artery occlusion) when given 4.5 to 24 hours after symptoms start. Patients will then be moved to a hospital that can remove the clot. The goal is to see if the drug improves recovery.
BeijingAges 18 years+ - NCT07208097Recruiting
Brain bleed clot dissolving with tNK for stroke recovery
This trial tests a clot-busting drug called tenecteplase given directly into the brain bleed through a thin tube. It may help reduce damage and improve recovery for people with a certain type of brain hemorrhage.
Suzhou, AnhuiAges 18–80 - NCT07271342Recruiting
Tracking tenecteplase for stroke in real-world settings
This study is collecting information on stroke patients who received the clot-dissolving drug tenecteplase. It aims to see how well the drug works and how safe it is in everyday hospital care in China.
BeijingAges 18 years+ - NCT07375966RecruitingPhase 2
Repeated clot-busting drug for stroke with large vessel block
This trial tests if giving a second dose of the clot-busting drug tenecteplase can help people whose stroke symptoms don't improve after the first dose, when a large or medium artery in the brain is still blocked. It may be an option for patients who cannot have a mechanical clot removal procedure.
Shenyang, LiaoningAges 18–80 - NCT07375953RecruitingPhase 2
Repeated clot-busting drug for stroke within 3 hours
This trial tests if giving a second dose of a clot-busting drug (tenecteplase) helps people who had a stroke and didn't improve much after the first dose. You must receive the second dose within 4.5 hours of your stroke symptoms starting.
Shenyang, None SelectedAges 18–80 - NCT06781385Enrolling by invitationPhase 2
Tenecteplase after clot removal for severe stroke
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
Charlotte, North CarolinaAges 18 years+ - NCT07369999RecruitingPhase 3
Butylphthalide plus tenecteplase for mild disabling stroke
This trial tests whether adding butylphthalide (a drug that improves blood flow) to the standard clot-busting medicine tenecteplase can help people with mild but disabling strokes recover better. If you have had a mild stroke within the last 4.5 hours and are 18–80, this study might be an option for you.
Changsha, HunanAges 18–80
What Tenecteplase is being studied for
Conditions with recruiting Tenecteplase studies.
Common questions
- Are there clinical trials studying Tenecteplase?
- Yes. Clin2 currently lists 40 recruiting studies that include Tenecteplase, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Tenecteplase trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Tenecteplase an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Tenecteplase or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.