Study of allopregnanolone for treating depression and pain after brain injury
Part of Brain & nervous system, Injuries & trauma, Pain clinical trials.
This study tests a new treatment called allopregnanolone for veterans who have both a past mild traumatic brain injury and current depression, along with chronic pain. The goal is to see if this treatment can improve mood and reduce pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- U.S. military service since 9/11/01 (OEF/OIF/OND era)
- A mild traumatic brain injury (concussion) since 2001
- Current major depression (moderate or greater)
- Ongoing muscle or bone pain rated at least 4 on a 0-10 scale
- No recent use of certain medications like benzodiazepines, opioids, or oral steroids
- No history of seizures, stroke, prostate cancer, or serious heart disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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