Quizartinib with chemotherapy for new or returning leukemia
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a combination of anti-leukemia drugs (including quizartinib) together with chemotherapy for people with acute myeloid leukemia (AML), a rare mixed-type leukemia, or high-risk myelodysplastic syndrome (MDS). It may help by trying to better control cancer in people whose disease is newly diagnosed or has returned/not responded to prior treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have AML, acute biphenotypic leukemia, or high-risk MDS (high blast count in bone marrow)
- Your age fits the group: 18–65 if newly diagnosed, or 18+ if your disease has relapsed or not responded
- If newly diagnosed with AML/MDS: you have not had chemotherapy before (some limited exceptions like certain short-term medicines are allowed)
- Your heart function test looks good: left ventricular ejection fraction is at least 50%
- Your blood and organ labs are within limits (kidney, liver, and certain electrolytes like potassium and magnesium)
- You can swallow and take pills, and you can sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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