Testing a numbing medicine to improve back decompression outcomes
Treatments studied
Part of Bones, joints & muscles clinical trials.
This Phase 2 study looks at whether a long-lasting local pain medicine (liposomal bupivacaine) can improve recovery and outcomes after surgery for lumbar stenosis (narrowing in the lower spine). You may be considered if you’re an adult needing decompression surgery and do not have reasons that would make surgery unsafe or different from the study’s plan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult age 18 or older
- You have lumbar stenosis (narrowing in the lower spine)
- You are not pregnant
- You are not breastfeeding
- You do not need instrumented fusion as part of your surgery
- You do not have certain key situations like severe health problems preventing surgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
This trial compares outcomes after decompression surgery for one affected area in the lower back, with and without adding spinal fusion. It may help patients avoid unnecessary extra surgery—or ensure fusion is used when it’s needed.
This study compares two surgical approaches for patients with lumbar spinal stenosis (a narrowing of the spine that puts pressure on nerves). One group will get standard decompression (relieving pressure), the other group will get that plus screws and rods to stabilize the spine. The goal is to see which leads to better outcomes.
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
This Phase 3 study compares two combinations of anesthesia and pain medications during lumbar decompression surgery, to see which helps more. It may help patients by aiming for better pain control and recovery using one planned medication approach.
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