Clinical trials
Lumbar Spinal Stenosis clinical trials
Below are recruiting lumbar spinal stenosis clinical trials, each written for real people, not researchers. We’re tracking 74 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07776366Recruiting
Study of disc protein levels and disc wear
This study looks at a protein called periostin in the discs of the lower back to see if it relates to how worn down the discs are, which might help improve future treatments.
Daegu, DaeguAges 20–80 - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+ - NCT07469020Recruiting
Cle-pad study: Checking leg artery health in spine surgery patients
This study is looking at how common blockages in leg arteries (peripheral artery disease, or PAD) are in people who are having surgery for lumbar spinal stenosis or had surgery less than 3 months ago. If you qualify, it may help doctors better understand and treat this condition.
LilleAges 18 years+ - NCT06075979Recruiting
Microbes and spine health: a surgical study
This study looks at whether certain microbes (tiny living things) are linked to spine problems like herniated discs or narrow spinal canals. It involves people who need spine surgery, and the findings might help explain why some spines wear out faster.
Jinan, ShandongAges 18–85 - NCT06407063Recruiting
Long-term results after surgery for lumbar spinal stenosis
This study looks at patients who had back surgery for lumbar spinal stenosis and a condition called spondylolisthesis between 2007 and 2015. They want to see how many people needed another operation years later.
TromsøAges 18 years+ - NCT06935201Recruiting
Digital rehab program for spinal stenosis surgery recovery
This study tests a digital, person-centered rehab program to help people recovering from surgery for lumbar spinal stenosis become more physically active. It aims to see if an online program can improve recovery and quality of life after surgery.
StockholmAges 18 years+ - NCT03553186RecruitingPhase 3
Tranexamic acid to reduce bleeding in spine surgery
This Phase 3 trial tests whether tranexamic acid can reduce bleeding during major spine fusion surgery for adults with scoliosis or spine degeneration. It may help lessen blood loss and the need for transfusions, while monitoring safety.
New York, New YorkAges 18–80 - NCT06089746Recruiting
Posture therapy for older veterans with spinal stenosis
This trial tests a non-invasive posture therapy for older veterans with lumbar spinal stenosis (a narrowing in the lower spine). It aims to reduce pain and improve walking without surgery.
Baltimore, MarylandAges 55–80 - NCT06907849Enrolling by invitationPhase 2
Imaging amyloid in spinal stenosis and carpal tunnel
This trial tests a special scan that uses a radioactive tracer to look for amyloid protein deposits in people who have had surgery for lumbar spinal stenosis (narrowing of the spine in the lower back) or carpal tunnel syndrome. The goal is to see if the scan can detect these deposits, which may be linked to ongoing orthopedic issues.
Knoxville, TennesseeAges 60 years+ - NCT04075539RecruitingPhase 3
At-home cycling for lumbar spinal stenosis pain
This study tests whether an at-home cycling program can reduce leg and back pain caused by lumbar spinal stenosis. It aims to see if regular, supervised cycling helps people walk and function better.
Paris, Île-de-France RegionAges 50 years+ - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT04407338Recruiting
B-DYN device versus standard fusion for lumbar stenosis
This trial compares a specific spinal fusion approach (B-DYN) with the standard fusion surgery for people with lumbar spinal stenosis. It aims to improve function after surgery and check whether the newer approach is well tolerated.
BordeauxAges 40 years+ - NCT04467944Recruiting
Lumbar fusion outcomes with arthritis in nearby spine segments
This study looks at how well lumbar fusion surgery works long-term when the joint just above or below (adjacent segment) already shows wear-and-tear. It may help predict who benefits most and guide treatment planning.
Beijing, Beijing MunicipalityAges 18–80 - NCT04469387Recruiting
Reduce adjacent back pain after lumbar surgery
This trial looks at whether a limited decompression (a careful nerve-space “freeing” procedure) can help prevent future problems in the spinal level next to your planned surgery. It targets people with spinal canal narrowing next to the surgery level but who do not yet have symptoms there.
Beijing, Beijing MunicipalityAges 18–80 - NCT04540068Recruiting
Predicting whether a sciatica procedure will work
This study looks for ways to predict how well a specific sciatica procedure (TEI) will help. If you have one-sided nerve pain from the low back, the trial may help personalize treatment so you’re less likely to go through ineffective care.
HaarlemAges 18 years+ - NCT04552145Recruiting
Physical therapy versus surgery for lumbar spinal stenosis
This study compares physical therapy to surgery to help relieve symptoms from narrowing in the lower spine. It looks at which treatment works best for walking discomfort caused by spinal stenosis.
LillehammerAges 50–80 - NCT04992572RecruitingEarly Phase 1
Comparing two types of anesthesia for back decompression surgery
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
Redwood City, CaliforniaAges 40–95 - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT05058287RecruitingPhase 3
Steroid shot during low-back surgery
This trial tests whether using a steroid medicine (a steroid shot) around the time of low-back decompression surgery improves pain and recovery. It is for adults having a limited-area laminectomy, and it compares steroid use versus not using it.
New York, New YorkAges 18–85 - NCT05253326Recruiting
Relaxing muscle exercises after spine surgery
This trial tests whether a structured “progressive muscle relaxation” routine can reduce pain and help recovery after spine surgery. You may be asked to learn and practice the relaxation steps even if you’ve never done them before.
Istanbul, ÜsküdarAges 18 years+ - NCT05273879Recruiting
Testing whether one-level fusion is needed after lumbar decompression
This trial compares outcomes after decompression surgery for one affected area in the lower back, with and without adding spinal fusion. It may help patients avoid unnecessary extra surgery—or ensure fusion is used when it’s needed.
Moscow, MoscowAges 45–75 - NCT05527145Recruiting
Non-surgical spacer for spinal stenosis causing leg pain
This trial tests a minimally invasive (“through the skin”) procedure that places a small spacer between back bones to relieve lumbar spinal stenosis symptoms like leg pain when walking. It may help people who still need surgery based on their symptoms and MRI findings but may be treated without open surgery.
RomeAges 50–85 - NCT06034405Recruiting
Checking spine tissue for heart amyloidosis signs
This trial is looking at leftover tissue from past spine surgeries to see if it contains signs of a heart condition called TTR amyloidosis. It may help find people who have this condition early.
Beverly Hills, CaliforniaAges 50 years+ - NCT06057428Recruiting
Activity levels in seniors having spine surgery
This study is tracking how active people are before and after surgery for lumbar spinal stenosis (a common cause of back and leg pain in older adults). It aims to see if activity monitoring can help improve recovery.
KøgeAges 65 years+
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Lumbar Spinal Stenosis trials by city
Studies with a site in or near these metro areas.
Lumbar Spinal Stenosis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for lumbar spinal stenosis?
- Yes. Clin2 currently lists 74 recruiting lumbar spinal stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar spinal stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar spinal stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.