Belatacept to protect kidneys in heart transplant patients
Treatments studied
Part of Heart & circulation, Immune system & allergy, Kidney & urinary clinical trials.
This trial studies whether belatacept can be used after a heart transplant to help protect kidney function over time. It focuses on people who already have (or are at risk for) worsening kidney function after transplant, while avoiding those with certain infections or rejection concerns.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and had a heart transplant at least 3 months ago
- You do not have donor-specific antibodies at the start of the study (an antibody test should be below the trial’s threshold)
- Your kidney function is poor or declining: estimated GFR is under 30 mL/min or it dropped by more than 50% since transplant
- You are Epstein-Barr virus positive on a blood test, and you received induction medicine (anti-lymphocyte serum) after transplant
- You must be able to understand the study and follow study visits and procedures; you must have signed consent
- For pregnancy-capable participants: pregnancy test must be negative and you must use effective contraception during the study and for 6 weeks after
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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