Clin2
NCT04198766Possibly a fitRecruiting

New OX40 immunotherapy for advanced solid tumors

Solid TumorNon-Small Cell Lung CancerHead and Neck CancerMelanomaGastric CancerRenal Cell CarcinomaUrothelial CarcinomaResectable Non-Small-Cell Lung Cancer

Treatments studied

Part of Cancer, Digestive system, Ear, nose & throat, Kidney & urinary, Lungs & breathing, Mouth & dental, Skin, Women’s health & pregnancy clinical trials.

This trial tests a new immunotherapy drug (INBRX-106) alone or with Keytruda (pembrolizumab) for adults with advanced solid tumors that have not responded to standard treatments. The goal is to see if the drug can help the immune system fight cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
340 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have a locally advanced or metastatic solid tumor that has not responded to or is not eligible for standard treatments
  • Your tumor type is one of the following: non-small cell lung cancer, melanoma, head and neck cancer, stomach/esophageal cancer, kidney cancer, bladder cancer, or a tumor with high MSI, high TMB, or MMR deficiency
  • You have not previously taken a drug targeting OX40
  • You do not have an active autoimmune disease or immune system condition requiring steroids or other immune-suppressing drugs

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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