One vs two radiation treatments for spine metastases
Part of Bones, joints & muscles, Cancer, Pain clinical trials.
This trial tests whether giving radiation to a spine metastasis in one dose works as well as giving it in two smaller doses. It aims to control tumors while keeping side effects and risk to the spinal cord low.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cancer spread to the spine in the middle-to-lower back (C3 to L5).
- The spine tumor spots are limited—either one spot, up to two connected spine levels, or up to three separated spots (with no more than two connected levels).
- Your general health is good enough to do daily life activities (Karnofsky score 70 or higher).
- There is no spinal cord compression (if there is epidural tumor, it must not be pressing on the spinal cord).
- The tumor is not in the very top neck (C1-2) or at the very bottom near the tailbone (S1-coccyx), and there’s no spine instability or mechanical problems.
- You can have MRI with contrast and return for follow-up scans, and doctors can safely give the radiation plans (either 18 Gy once or 24 Gy in two doses).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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