MRI scans to predict normal-tissue side effects after treatment
Part of Cancer, Injuries & trauma, Mouth & dental clinical trials.
This trial uses repeated MRI scans to better predict which patients may develop painful jaw and mouth tissue problems after radiation and/or certain bone or blood-vessel medicines. It may help clinicians spot problems earlier and tailor follow-up care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be over 18 years old
- You need to be able to do normal daily activities (ECOG 0–2)
- You must be willing to sign written informed consent
- You either have (1) an oral cavity/oropharynx/skull base cancer treatment plan involving radiation and/or certain medicines, or (2) you already have ORN or MRONJ
- You must be able to have the specific MRI types used in the study (DW-MRI and DCE-MRI)
- You should be able to safely have MRI (no non-MRI-safe metal implants), and your kidney function must be adequate (GFR 30 or higher)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses special MRI scans with contrast to better detect osteoradionecrosis (jaw bone injury) after radiation for head and neck cancer. If you qualify, the scans may help your team diagnose problems earlier and choose the right next treatment.
This study uses special MRI scans before and after radiation therapy to see if they can predict damage to your jawbone. If you are getting radiation to the head or neck area, this study may help monitor side effects.
This trial is studying how MRI images can help predict response to a combination of chemotherapy and immunotherapy before surgery for head and neck cancer. It aims to improve treatment planning for patients with this type of cancer.
This study tests whether delaying radiation therapy can help doctors learn more from MRI scans and immune system changes in patients with head and neck cancer. This could lead to better treatment decisions.
This study uses repeat MRI scans to look for imaging “markers” that may help doctors better understand head and neck squamous cell cancer. It may be most relevant if you are planning curative surgery and/or (chemo)radiotherapy and can safely undergo MRI more than once.
This trial tests special MRI scans to find warning signs of cancer that has returned or spread in the head and neck area. It may help doctors see these changes more clearly, which could improve treatment planning.
Hear when a new Osteoradionecrosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.