Bone marrow transplant for inherited immune system disorders
Treatments studied
Part of Blood & lymphatic, Immune system & allergy, Infections clinical trials.
This trial studies how well a donor bone marrow (stem cell) transplant works for people with inherited immune system problems (called immune deficiencies). It’s for patients who haven’t improved with usual treatment or don’t have another good option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between age 4 and 69, and you weigh at least 12 kg (about 26 lb).
- You have an inherited immune problem (a known genetic cause or a typical history of immune problems like repeated infections or immune over-activity).
- A suitable donor is available: a closely matched family donor, matched unrelated donor, or a “half-match” related donor.
- Your heart, lung, liver, and kidney health are strong enough for transplant treatment.
- You (or your parent/guardian for children) can understand and sign consent, and children can agree (assent).
- You can travel to and stay near the NIH for at least 100 days after transplant, with an adult caregiver if needed early on.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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