Steroid medicines for high-risk heart surgery patients
Part of Heart & circulation clinical trials.
This trial tests whether adding two common medicines, hydrocortisone and fludrocortisone, to standard care can help people who are at higher risk during planned heart surgery. It aims to see if this combination can reduce serious complications after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- Your heart surgery is planned (not an emergency) and you are considered at intermediate or high risk (a score of more than 4 on the EuroSCORE II).
- The surgery is one of these types: coronary artery bypass, aortic valve replacement, mitral valve repair or replacement, surgery on the aortic root, or a combination of these.
- Your surgery will use a heart-lung machine (cardiopulmonary bypass).
- You are not currently on long-term steroid medication, and you do not have an autoimmune or chronic inflammatory condition.
- You are not pregnant, not on dialysis for kidney failure, and have not had heart surgery before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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