Clin2
NCT05320198Possibly a fitRecruiting

Testing DISC-0974 for anemia in myelofibrosis or MDS

Myelofibrosis; AnemiaAnemiaMyelofibrosisMyelofibrosis Due to and Following Polycythemia VeraPrimary MyelofibrosisPost-essential Thrombocythemia MyelofibrosisMyelodysplastic Syndromes

Part of Blood & lymphatic clinical trials.

This trial tests an investigational drug called DISC-0974 for people with myelofibrosis or certain types of MDS who have low red blood cell counts (anemia). The goal is to see if this treatment can help improve anemia and reduce the need for blood transfusions.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
150 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 18 years old.
  • You have myelofibrosis (with a certain risk score) or a lower-risk type of MDS, confirmed by a recent bone marrow biopsy.
  • You have anemia, meaning your hemoglobin is below 10 g/dL or you need regular blood transfusions.
  • You have not taken certain anemia treatments (like androgens, EPO, or luspatercept) in the last 28 days.
  • You are not planning to have a stem cell transplant within the next 8 months.
  • Your kidney and liver function are within acceptable limits based on blood tests.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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