TIF surgery after successful Barrett’s ablation
Part of Cancer, Digestive system clinical trials.
This trial looks at outcomes after a procedure called TIF to help control reflux after Barrett’s esophagus has been fully treated with endoscopic ablation. You might benefit if you still have abnormal acid reflux and want an option other than lifelong acid-suppressing medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 75 years old
- You previously had Barrett’s esophagus confirmed by biopsy (with or without dysplasia)
- Your Barrett’s was fully cleared after ablation (radiofrequency or cryotherapy) on two checkups at least 3 months apart, and the most recent check was within 6 months
- You have abnormal acid reflux on a test called Bravo pH monitoring (acid exposure time over 6% over 48–96 hours)
- You have a small hiatal hernia (2 cm or less) or your valve function is not too severe (Hill grade under 2)
- You take a proton pump inhibitor (PPI) medication but prefer an intervention instead of staying on lifelong pills
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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