Radiofrequency ablation effects on the esophagus

This study compares two endoscopic treatments to remove abnormal cells in Barrett’s esophagus and lower the chance of it worsening. If you qualify, you may be assigned to one of the two procedures and followed to see how well they work and how safe they are.

This trial tests if adding the antifungal drug itraconazole to standard ablation therapy can help prevent esophageal cancer in people with high-risk Barrett's esophagus. You must have a confirmed diagnosis of Barrett's esophagus with low- or high-grade dysplasia or early-stage cancer, and be planning to have ablation treatment.

This study looks at people with Barrett's esophagus who are about to have a procedure to remove a suspicious spot. It tests a new way to predict if cancer might come back, and it checks how learning your risk affects your worry and quality of life.

This study tests a less invasive way to check for Barrett's esophagus and esophageal cancer. Instead of a standard endoscopy, they may use a sponge-on-a-string or other simpler methods, which could be more comfortable and easier for patients.

This study compares two approaches for people with Barrett's esophagus and low-grade dysplasia: regular surveillance (monitoring with endoscopies) versus endoscopic treatment to remove the abnormal cells. It aims to see which approach is better at preventing progression to more serious conditions.

This study tests less invasive ways to detect high-grade dysplasia (very abnormal cells) and esophageal cancer in people with Barrett's esophagus, a condition that can increase cancer risk. It looks for these changes using cell samples taken during a routine endoscopy, which may be quicker and more comfortable than standard biopsies.