Radiofrequency ablation effects on the esophagus

This study compares two endoscopic treatments to remove abnormal cells in Barrett’s esophagus and lower the chance of it worsening. If you qualify, you may be assigned to one of the two procedures and followed to see how well they work and how safe they are.

This trial tests if adding the antifungal drug itraconazole to standard ablation therapy can help prevent esophageal cancer in people with high-risk Barrett's esophagus. You must have a confirmed diagnosis of Barrett's esophagus with low- or high-grade dysplasia or early-stage cancer, and be planning to have ablation treatment.

This trial tests a new risk model to predict if early Barrett's esophagus-related cancer may return. It also looks at how telling patients their risk affects their quality of life and fear of cancer. If you have Barrett's with a small, early cancer, this study may help decide the best follow-up plan for you.

This study tests a new, less invasive way to detect precancerous changes or early cancer in Barrett's esophagus. It uses a sponge or brush to collect cells from your esophagus during a routine endoscopy, which may help find problems earlier and avoid more invasive procedures.

This trial tests two simple, non-surgical methods to look for Barrett's esophagus (a change in the lining of the swallowing tube) and early esophageal cancer. It is for people who are at higher risk or lower risk, but have never had Barrett's or cancer before.

This study looks at the link between GERD (chronic acid reflux) and Barrett's esophagus, a condition where the lining of the esophagus changes. If you have GERD, joining could help doctors understand who might develop Barrett's and how to catch it early.