EndoRotor vs radiofrequency treatment for Barrett’s esophagus
Part of Cancer, Digestive system clinical trials.
This study compares two endoscopic treatments to remove abnormal cells in Barrett’s esophagus and lower the chance of it worsening. If you qualify, you may be assigned to one of the two procedures and followed to see how well they work and how safe they are.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult with Barrett’s esophagus that measures about 2 to 6 cm for the “tongue” part (and overall within the study’s size range).
- Your biopsies show low-to-high grade dysplasia, or you previously had a superficial (non-invasive) esophageal cancer removed, and it has been checked by pathology.
- You can give consent and sign the study consent form (French-speaking and able to read).
- You can take proton pump inhibitors (PPIs) by mouth.
- You do not have significant esophagus narrowing that prevents the doctor from passing a standard scope.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how radiofrequency ablation (RFA) affects the flexibility and lining of the esophagus in people with Barrett's esophagus and early cancer. It may help doctors understand how this treatment works.
This trial compares two approaches for people with Barrett’s esophagus and low-grade dysplasia: regular monitoring versus treatment done through an endoscopy. It aims to see which approach is safer and better at preventing progression to more serious changes in the esophagus.
This trial tests a device that collects cells from the esophagus using a swallowed capsule, which may detect Barrett's esophagus without a standard endoscopy. It is for people who are already scheduled for an endoscopy.
This study tests a new, less invasive way to detect precancerous changes or early cancer in Barrett's esophagus. It uses a sponge or brush to collect cells from your esophagus during a routine endoscopy, which may help find problems earlier and avoid more invasive procedures.
This trial tests a new risk model to predict if early Barrett's esophagus-related cancer may return. It also looks at how telling patients their risk affects their quality of life and fear of cancer. If you have Barrett's with a small, early cancer, this study may help decide the best follow-up plan for you.
This study is testing whether it's safe to stop regular surveillance endoscopies for people with low-risk Barrett's esophagus. If you have a short Barrett's segment without any dysplasia, you may be able to avoid future procedures.
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