EndoRotor vs radiofrequency treatment for Barrett’s esophagus
Part of Cancer, Digestive system clinical trials.
This study compares two endoscopic treatments to remove abnormal cells in Barrett’s esophagus and lower the chance of it worsening. If you qualify, you may be assigned to one of the two procedures and followed to see how well they work and how safe they are.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult with Barrett’s esophagus that measures about 2 to 6 cm for the “tongue” part (and overall within the study’s size range).
- Your biopsies show low-to-high grade dysplasia, or you previously had a superficial (non-invasive) esophageal cancer removed, and it has been checked by pathology.
- You can give consent and sign the study consent form (French-speaking and able to read).
- You can take proton pump inhibitors (PPIs) by mouth.
- You do not have significant esophagus narrowing that prevents the doctor from passing a standard scope.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how radiofrequency ablation (RFA) affects the flexibility and lining of the esophagus in people with Barrett's esophagus and early cancer. It may help doctors understand how this treatment works.
This study compares two approaches for people with Barrett's esophagus and low-grade dysplasia: regular surveillance (monitoring with endoscopies) versus endoscopic treatment to remove the abnormal cells. It aims to see which approach is better at preventing progression to more serious conditions.
This trial tests a device that collects cells from the esophagus using a swallowed capsule, which may detect Barrett's esophagus without a standard endoscopy. It is for people who are already scheduled for an endoscopy.
This study tests less invasive ways to detect high-grade dysplasia (very abnormal cells) and esophageal cancer in people with Barrett's esophagus, a condition that can increase cancer risk. It looks for these changes using cell samples taken during a routine endoscopy, which may be quicker and more comfortable than standard biopsies.
This study is testing whether it's safe to stop regular surveillance endoscopies for people with low-risk Barrett's esophagus. If you have a short Barrett's segment without any dysplasia, you may be able to avoid future procedures.
This study looks at people with Barrett's esophagus who are about to have a procedure to remove a suspicious spot. It tests a new way to predict if cancer might come back, and it checks how learning your risk affects your worry and quality of life.
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