Testosterone plus walking training to support bones and muscles
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system, Hormones & metabolism, Injuries & trauma, Kidney & urinary clinical trials.
This Phase 2 study tests whether testosterone therapy combined with walking training can improve bone and muscle health after a spinal cord injury. It aims to help men with low testosterone and walking problems by improving strength, body composition, and related health markers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a man over 18 years old
- You have a spinal cord injury (SCI) that is either incomplete above L1, or complete from T2 to L1, and you’ve had spasticity (stiffness) for over 60 days
- Blood tests show low testosterone (or low related forms of testosterone)
- You have signs or symptoms that can happen with low testosterone (example: low sex drive, erectile problems, low energy, mood changes, hot flashes, low muscle/strength, or low bone health)
- You can walk in testing: your usual pace is very slow, or a bit faster but you need a brace/device or have very impaired movement (checked with a timed walking test)
- You are willing and medically cleared to take testosterone as directed and follow the study rules
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether testosterone therapy, alone or with finasteride, can improve walking and other functions in veterans with spinal cord injury and low testosterone. It may help with energy, strength, and quality of life.
This study tests whether testosterone therapy can improve brain and nerve function in men with low testosterone who have had a spinal cord injury for more than a year. It involves three visits over 30 days and may help with thinking, mood, or other nerve-related issues.
This study looks at whether low testosterone affects blood vessel health in men with recent spinal cord injury. It tests if testosterone replacement can help improve blood vessel function.
This study tests whether using a powered walking exoskeleton together with a mild spinal cord stimulation device can improve muscle and bone strength in people with long-term spinal cord injuries. If you qualify, you'd use the exoskeleton during therapy sessions while researchers watch for changes in your leg muscles and bones.
This study tests a new way to help people with spinal cord injuries walk better. If you join, you'll practice walking on a treadmill with support, which may improve your strength and speed over time.
This study tests a special walking program for people who have recently had a spinal cord injury. The goal is to help you recover as much walking ability as possible.
Hear when a new Spinal Cord Injuries trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.