Stop blood-thinner therapy after PFO closure in younger stroke patients
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This trial tests whether it’s safe to stop antithrombotic (blood-thinner) treatment after a successful hole-in-the-heart procedure (PFO closure) in people age 60 and under who had an unexplained stroke or TIA. It may help some people avoid long-term blood-thinner side effects if their risk stays low.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 60 years old or younger
- You had a successful PFO closure procedure using an approved device
- Your stroke or TIA was “cryptogenic,” meaning the cause wasn’t found, and you meet the study’s scoring (RoPE score 6 or higher)
- After the PFO closure, there is no moderate-or-higher leftover leak (residual shunt must be less than moderate)
- You do not have atrial fibrillation after the PFO closure and have not had another stroke/TIA within 1 year
- You can have an MRI if needed and can sign informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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