Treatment of stroke from PFO, with or without closure
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This study looks at whether treating a history of “cryptogenic” stroke (stroke with no clear cause) using a patent foramen ovale (PFO) closure, plus medical therapy, is better than medical therapy alone. It focuses on people over 60 with a heart shunt seen on an ultrasound of the heart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a cryptogenic stroke (no clear cause found).
- You are older than 60 years.
- Your heart ultrasound showed a right-to-left shunt through a PFO.
- You can take anti-platelet medicines like aspirin or clopidogrel safely.
- You do not have major heart or artery problems that make treatment unsafe (as judged by echo/ultrasound).
- You can attend follow-up visits and give consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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