A study of closing a PFO to prevent strokes
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This trial looks at the safety and results of closing a PFO (a small hole in the heart) in people who have had a stroke or embolism with no other clear cause. If you qualify, doctors will close your PFO using a small tube inserted through a blood vessel and then follow your health over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You have had a stroke, mini-stroke, or other organ embolism with no clear cause, and a PFO was found.
- You are able to take blood-thinning medications safely.
- You are not in the middle of an active infection or other severe illness.
- You do not have other serious heart conditions, such as blood clots in the heart or severe valve disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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Other trials that look related to this one.
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
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This trial tests whether closing a hole in the heart (a PFO) with a special device can help prevent another stroke after an unexplained stroke. You may be a candidate if your stroke likely happened because blood can pass through this PFO.
This study looks at how well patients do over time after having a hole in their heart (patent foramen ovale, or PFO) closed with a small device inserted through a vein. It may help doctors understand the benefits and risks of the procedure.
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This trial studies the best way to prevent another stroke after a recent stroke in people ages 60 to 80 who have a “PFO” heart connection. It compares closing the PFO vs taking mouth blood-thinners or antiplatelet medicine, based on what your doctors determine is safest for you.
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