How ofloxacin levels may affect older adults with bone infections
Treatments studied
Part of Bones, joints & muscles, Infections clinical trials.
This study looks at whether blood levels of the antibiotic ofloxacin in people over 65 are linked to side effects, in older adults hospitalized for bone and joint infections. It may help doctors choose safer doses, especially when switching from IV treatment to pills.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 66 or older and currently hospitalized at the University Hospital of Amiens
- Have an uncomplicated bone or joint infection (not complicated by other issues)
- Have a plan to switch from IV antibiotics to oral ofloxacin (pills)
- Be willing to participate in the study
- No known liver or bile duct injury or damage
- No allergy or other reason you cannot take ofloxacin
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how the antibiotic rifampin behaves in the body when used to treat staph infections in bones or joints. It may help doctors better dose the drug for future patients.
This study looks at how best to dose certain antibiotics in people age 75 and older who are admitted to a geriatric (older-adult) hospital unit. It aims to measure antibiotic levels in the body to see whether dosing can be improved for older patients.
This trial tests whether adding a drug called probenecid can help amoxicillin work better in your body for treating bone and joint infections. If you are already taking amoxicillin for such an infection, adding probenecid might increase the amount of amoxicillin in your blood, potentially making the treatment more effective.
This study measures how much of the antibiotic delafloxacin gets into skin, soft tissue, and bone in people with serious infections. It may help doctors understand if the drug reaches the infection site well enough to be effective.
This trial looks at whether having a urinary tract infection or bacteria in urine affects recovery after bone surgery. It focuses on people 65 and older who will have surgery for a broken bone or other bone problem.
This study aims to customize anti-infection medication doses for people with bone or joint infections. The goal is to make treatment more effective and reduce side effects.
Hear when a new Bone and Joint Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.