Delafloxacin levels in skin, soft tissue, and bone infections
Part of Bones, joints & muscles, Infections, Lungs & breathing clinical trials.
This study measures how much of the antibiotic delafloxacin gets into skin, soft tissue, and bone in people with serious infections. It may help doctors understand if the drug reaches the infection site well enough to be effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- Your kidney function must be good enough (eGFR over 80).
- You must be receiving delafloxacin through an IV for a serious skin or soft tissue infection.
- You must have either a wound infection after heart surgery, or an infected joint replacement that needs surgery.
- You cannot have taken other quinolone antibiotics (like ciprofloxacin or levofloxacin) in the week before starting the study.
- You must agree to have blood drawn at five different times during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how the antibiotic rifampin behaves in the body when used to treat staph infections in bones or joints. It may help doctors better dose the drug for future patients.
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
This study tests whether adding the antibiotic rifampicin to standard treatment works better than standard treatment alone for staph infections in hip or knee replacements. The goal is to find a more effective way to clear the infection and avoid more surgeries.
This trial tests if injecting levofloxacin (a type of antibiotic) just under the skin around the surgical cut helps prevent infections in emergency belly surgery. If you are having an emergency operation on your abdomen and your surgery is considered contaminated or dirty (like from a burst appendix or a bowel perforation), you may be eligible.
This study looks at whether blood levels of the antibiotic ofloxacin in people over 65 are linked to side effects, in older adults hospitalized for bone and joint infections. It may help doctors choose safer doses, especially when switching from IV treatment to pills.
This study tests if a drug called sitafloxacin can quickly kill mycobacterium abscessus bacteria in the lungs. It may help people with this hard-to-treat infection find a more effective treatment.
Hear when a new Soft Tissue Infections trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.