Nerve block injections for long-lasting nerve cough
Part of Lungs & breathing clinical trials.
This trial studies an office-based injection to calm a specific nerve in the neck to treat chronic cough that seems to come from nerve irritation (“neurogenic/sensory neuropathic” cough). It may help people whose cough has lasted at least 8 weeks and continues despite standard treatments for common cough causes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You can speak and understand English and provide your own consent.
- Your cough has lasted 8 weeks or longer, and it seems triggered like nerve irritation (for example by smells, temperature changes, tickling, or throat irritation).
- Your cough has not improved after standard treatments for common causes: reflux, asthma, and allergies/upper airway problems.
- You must NOT have a different known cause for cough (such as reflux disease, asthma, allergic rhinitis, or COPD) as the main reason.
- You must not start new “nerve medicine” at the time of the injection (but stable doses of gabapentin or amitriptyline may be allowed).
- You cannot have had a Nissen fundoplication within the last year, and you cannot have smoked in the last 5 years.
- You need to be able to safely receive bupivacaine and Kenalog-40 (no allergy to these medicines).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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