Clin2
NCT04649008Possibly a fitRecruiting

MRI and brain electrodes to map epilepsy areas

EpilepsyEpilepsy IntractableEpilepsy, Temporal Lobe

Part of Brain & nervous system clinical trials.

This early study looks at how MRI scans and implanted brain electrodes (intracranial EEG) can pinpoint where seizures start, especially in the temporal (side) lobe. It may help doctors better localize seizure sources for people whose seizures don’t respond well to medications.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
290 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have epilepsy that has not improved enough with seizure medicines
  • Your doctors are planning to place intracranial EEG electrodes (a more direct brain monitoring test)
  • Your epilepsy is thought to come from the temporal lobe (the side part of the brain)
  • You can safely have an MRI at 3 Tesla (3T), meaning no MRI-safety contraindications like certain metal implants and you can tolerate the scan
  • You do not have a situation that would make electrode monitoring unsafe or not possible (for example, pregnancy), and you have not had prior intracranial brain surgery or an implanted brain device that prevents this study
  • Your implanted-electrode results are expected to be able to show clear, diagnostic seizure onset areas

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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