Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 338 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07680842Recruiting
Non-invasive ultrasound for drug-resistant epilepsy
This study tests a non-invasive focused ultrasound treatment for people with epilepsy that doesn't respond to medications. The goal is to see if this gentle ultrasound can reduce seizures without surgery.
San Francisco, CaliforniaAges 21–65 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT07580183Recruiting
Memory and Brain Function in Epilepsy Surgery
This study examines how the brain recognizes spatial scenes (like rooms or landscapes) in people with epilepsy who may have surgery. Researchers want to understand memory patterns before and after surgery to help predict outcomes.
Sacramento, CaliforniaAges 18–55 - NCT06593951Recruiting
EPM1 natural history study
This study will follow people with EPM1 over time to better understand the disease. It is a registry, meaning you will share information through video calls and questionnaires, with no experimental treatments involved.
Boston, MassachusettsAges Any age - NCT06967727Recruiting
Registry study for epilepsy and movement disorders
This study is creating a registry to track the health of people who have specific genetic changes that cause epilepsy and uncontrolled movements (dyskinesia). It may help researchers better understand these conditions and how they change over time.
Boston, MassachusettsAges birth–30 years - NCT03478852Recruiting
Epilepsy screening and evaluation for people 8 and older
This study checks how people with known or suspected epilepsy are evaluated and followed. It may help by improving screening and understanding care for epilepsy in children and adults.
Bethesda, MarylandAges 8–110 - NCT04274179RecruitingPhase 3
Ketogenic diet for children with new childhood absence seizures
This trial tests whether a high-fat, low-carbohydrate (ketogenic) diet can reduce absence seizures in children who are newly diagnosed. It may help some kids by changing how the brain uses energy, but participation requires close diet monitoring and follow-up.
Baltimore, MarylandAges 3–12 - NCT05019885RecruitingPhase 2
IV ketamine for hard-to-treat epilepsy in adults
This Phase 2 study tests whether a low dose of IV ketamine can reduce seizures in adults with drug-resistant epilepsy. It may help people whose seizures continue despite trying at least two appropriate seizure medicines.
New York, New YorkAges 18 years+ - NCT06292494Recruiting
Focused ultrasound for drug-resistant epilepsy
This trial tests whether focused ultrasound can help people whose seizures are not controlled by two or more medications. You would have a noninvasive procedure while awake, pressing a stop button if needed, and your hair will be partially shaved.
TaipeiAges 18 years+ - NCT06492720Recruiting
Testing focused ultrasound for drug-resistant epilepsy
This study tests a new device called NaviFUS that uses focused sound waves to gently stimulate a small area of the brain. It is for people whose seizures start in one part of the brain and are not fully controlled by seizure medicines.
TaipeiAges 18–65 - NCT06608966Recruiting
Epilepsy Journey: Helping Teens Manage Daily Challenges
This study tests a program called Epilepsy Journey to help teenagers with epilepsy improve skills like planning, organizing, and staying on task. It is designed for teens who struggle with these thinking skills and live at home with a caregiver.
Orange, CaliforniaAges 13–17 - NCT07010445Recruiting
Gut-brain connection in resistant epilepsy
This study looks at how the gut and brain talk to each other in people with epilepsy, especially when seizures are hard to control. It may help find new ways to treat epilepsy by focusing on the gut.
Milan, LombardyAges 3–50 - NCT01273129Recruiting
Surgery for epilepsy that medicines cannot control
This trial looks at using brain surgery to treat epilepsy that does not improve with usual medicines, or epilepsy caused by a brain tumor. It may help some people reduce seizures if surgery is appropriate for their situation.
Bethesda, MarylandAges 8–99 - NCT07668856RecruitingPhase 3
CBD for children with hard-to-treat epilepsy
This trial tests if adding cannabidiol (CBD) to your child's current seizure medicines can reduce seizures. It uses a personalized approach to see if CBD works for each child.
Utrecht, UtrechtAges 1–18 - NCT07448233Enrolling by invitation
AI health management for epilepsy in rural areas
This trial tests a smartphone-based AI system to help manage epilepsy long-term in rural areas. It is for people who have had at least one convulsive seizure in the past year and can use a smartphone with a caregiver.
Xi'an, ShaanxiAges 18–65 - NCT07378397Enrolling by invitation
MEG brain mapping for epilepsy surgery in children
This study uses a safe brain scan (MEG) to help doctors plan epilepsy surgery for children. It aims to make surgery safer and more precise by mapping key brain areas beforehand.
Birmingham, United KingdomAges 6–15 - NCT06701084Recruiting
Genetic Causes of Infant Epilepsy at Boston Children's
This study looks at the genetic causes of epilepsy that starts in babies under 1 year old. It aims to learn how a genetic diagnosis might help guide care.
Boston, MassachusettsAges Any age - NCT06623994Recruiting
Epilepsy care access study in Kenya
This trial tests a program to help people with epilepsy in Kenya who are not taking their medication regularly get better access to care and support.
EldoretAges 12 years+ - NCT07716930Enrolling by invitation
Eye scan study for drug-resistant epilepsy
This study uses a special eye scan (OCT) to look for changes in the retina that might be linked to hard-to-control epilepsy. The goal is to find new biomarkers that could help doctors better understand and manage the condition.
IstanbulAges 18–40 - NCT07110454Recruiting
Long-term follow-up study for epilepsy monitoring implant
This study follows people who previously enrolled in the DETECT study and had a Minder device implanted to monitor brain activity. The goal is to see how the device performs over a longer period of time.
Phoenix, ArizonaAges 18–75 - NCT03865771Recruiting
Sleep study to improve memory in children with focal epilepsy
This study looks at how sleep affects memory in children with certain types of age-related focal epilepsy. It compares them to children hospitalized for non-nerve (non-neurologic) reasons to see whether sleep-related brain patterns relate to learning and memory.
NancyAges 6–13 - NCT03893916Recruiting
MEG vs EEG tests to find the epilepsy trigger before surgery
This study compares two brain tests—MEG and routine scalp EEG—to pinpoint where seizures start before surgery. It may help doctors choose the safest and most effective plan if you’re being considered for an epilepsy procedure.
BronAges 18–60 - NCT04559919Recruiting
Building a regional database for people with epilepsy
This study collects information about adults who have had an unprovoked seizure or who have epilepsy. The goal is to better understand epilepsy in the community and improve future care.
BoråsAges 18 years+ - NCT04649008RecruitingEarly Phase 1
MRI and brain electrodes to map epilepsy areas
This early study looks at how MRI scans and implanted brain electrodes (intracranial EEG) can pinpoint where seizures start, especially in the temporal (side) lobe. It may help doctors better localize seizure sources for people whose seizures don’t respond well to medications.
Philadelphia, PennsylvaniaAges 18 years+
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Epilepsy trials by city
Studies with a site in or near these metro areas.
Epilepsy trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 338 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.