Study how a heart opening and its flow link to stroke
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This study looks at the detailed flow pattern through a patent foramen ovale (PFO)—a small opening in the heart—and how it may relate to stroke, TIA, or migraine. Doctors use special ultrasound testing with contrast to better understand who is most affected.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 16 and 65 years old
- You have a confirmed PFO showing strong right-to-left flow on a bubble ultrasound test
- You fit one of these groups: recent ischemic stroke or TIA (within 6 months), long-term migraine, or no symptoms with an incidental PFO
- Your symptoms must not have another clear explanation besides the PFO
- You have no recent stroke/TIA in the last month
- You can safely have contrast used for the ultrasound test (no allergy)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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