Study of a new device to close a hole in the heart after a stroke
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have had a stroke that was caused by a blood clot, confirmed by brain scan.
- You have a PFO (a small hole in the heart) that lets blood flow from the right to the left side.
- You are able to walk and care for yourself (modified Rankin score of 3 or less).
- You do not have other clear causes for your stroke, such as severe artery disease or heart rhythm problems.
- You are not pregnant and agree to use birth control if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device to close a PFO (a small hole in the heart) in people who have had a stroke caused by a blood clot passing through that hole. The goal is to see if the device can prevent another stroke.
This trial tests whether closing a hole in the heart (a PFO) with a special device can help prevent another stroke after an unexplained stroke. You may be a candidate if your stroke likely happened because blood can pass through this PFO.
This trial looks at the safety and results of closing a PFO (a small hole in the heart) in people who have had a stroke or embolism with no other clear cause. If you qualify, doctors will close your PFO using a small tube inserted through a blood vessel and then follow your health over time.
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
This trial studies whether a Cera™ device is safe and effective for closing a patent foramen ovale (PFO), a small hole in the heart. It is for adults whose PFO is linked to certain types of stroke or ongoing clot-related events.
This trial compares two devices used to close a hole in the heart (called a PFO) in adults who have had a stroke or mini-stroke (TIA) within the last year. The goal is to see which device works better to prevent future strokes.
Hear when a new PFO trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.