Closing the hole in the heart for stroke and migraine prevention
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial tests a device called the Snowy PFO Closure System, which is meant to close a small hole in the heart (PFO) that can let blood clots pass to the brain and cause strokes or migraines. The device is inserted through a small tube, and the study aims to see if it is safe and works well.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have a small hole in the heart (PFO) that lets a moderate or large amount of blood leak between chambers.
- You have had an unexplained stroke, a transient ischemic attack (TIA), or you have chronic migraine.
- You are willing to sign a consent form and complete follow-up visits.
- You do not have certain other heart conditions, like irregular heartbeat, heart valve problems, or heart muscle disease.
- You have not had heart surgery before, and you do not have severe liver or kidney issues or an active infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
This trial tests a new device to close a PFO (a small hole in the heart) in people who have had a stroke caused by a blood clot passing through that hole. The goal is to see if the device can prevent another stroke.
This trial looks at the safety and results of closing a PFO (a small hole in the heart) in people who have had a stroke or embolism with no other clear cause. If you qualify, doctors will close your PFO using a small tube inserted through a blood vessel and then follow your health over time.
This trial tests whether closing a hole in the heart (a PFO) with a special device can help prevent another stroke after an unexplained stroke. You may be a candidate if your stroke likely happened because blood can pass through this PFO.
This trial tests whether closing a small hole in the heart (called a PFO) can help eliminate migraines. If you have frequent migraines and no other major health issues, this procedure might reduce or stop your headaches.
This study looks at the detailed flow pattern through a patent foramen ovale (PFO)—a small opening in the heart—and how it may relate to stroke, TIA, or migraine. Doctors use special ultrasound testing with contrast to better understand who is most affected.
Hear when a new Patent Foramen Ovale trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.