Placebo vs allergy medicine to prevent transfusion reactions
Part of Blood & lymphatic, Immune system & allergy clinical trials.
This trial tests whether an allergy medicine (chlorpheniramine) can prevent allergic reactions during blood transfusions. You might be placed in either the medicine group or a placebo (inactive pill) group to compare side effects and reaction rates.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old
- You have a blood disorder and need a blood product transfusion (red cells, platelets, or plasma)
- You can understand the study and sign consent
- You do not have a history of allergic diseases or frequent prior allergic transfusion reactions
- You have not taken steroid allergy medicines or allergy drugs within 24 hours before transfusion
- You have not had washed red blood cells, past bone marrow transplant, or certain serious heart or stroke-related problems
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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