Freezing tumor treatment plus targeted radiation for painful bone spread
Part of Cancer, Digestive system, Hormones & metabolism, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.
This study tests whether combining a “freezing” procedure (cryoablation) with focused external radiation (SBRT) can reduce pain from bone metastases. It’s for people with certain cancers that have spread to bone and are having significant pain in a specific bone spot.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a cancer diagnosis that has spread to the bone, shown on CT, MRI, or ultrasound
- The tumor type is one of the allowed cancers (kidney, bladder/urothelial, prostate that no longer responds to hormone therapy, sarcoma, thyroid, colorectal, or melanoma)
- You have one painful bone spot that can be treated with both freezing and SBRT, is 7 cm or smaller, and matches what imaging shows
- Your pain from that bone spot is at least 4 out of 10 (and should be linked to the visible tumor on scans)
- Your blood counts and clotting tests are high enough for the procedure (including platelets > 50,000 and INR < 1.5 within 6 weeks)
- You cannot have had radiation/ablation/surgery to that same target spot before, and you must not be pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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