Immune response and stroke treatment outcomes
Part of Brain & nervous system, Heart & circulation clinical trials.
This study looks at how your immune system reacts to stroke treatments like clot-busting drugs or mechanical clot removal. The goal is to see if immune markers can predict recovery, which could help tailor future stroke care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are having an acute ischemic stroke (a stroke caused by a blocked blood vessel in the brain).
- You are eligible for and will receive a standard stroke treatment: clot-busting medication (IV thrombolysis), mechanical clot removal (thrombectomy), or both.
- You are able to have an MRI of the brain (no pacemaker, no severe claustrophobia, etc.).
- You do not have a bleeding in the brain (intracranial hemorrhage) as seen on the first scan.
- You are not on immunosuppressive drugs or steroids at the time of admission.
- You do not have a pre-existing neurological disability (modified Rankin Scale > 2) or known dementia.
- You do not have a severe allergy to gadolinium (MRI contrast dye) or severe kidney failure (creatinine clearance < 15 mL/min).
- You are not pregnant or breastfeeding.
- You are covered by a social security system.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how the body’s immune system responds after an acute ischemic stroke that may be treated with a procedure called mechanical thrombectomy. It may help doctors understand what immune changes happen after treatment and improve future care.
This study looks at inflammation-related changes soon after an acute ischemic stroke (a type caused by a blocked blood vessel). It may help researchers understand what factors drive recovery and how they could be targeted in the future.
This trial checks if adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency clot removal can improve recovery for people with a severe stroke affecting the back part of the brain (posterior circulation). It is for patients who need urgent treatment within 24 hours of symptom onset.
This study looks for biological and imaging markers that may predict heart/vascular outcomes after an ischemic stroke. You may join if you are eligible for standard stroke treatment and can complete planned follow-up and MRI scans.
This study tests a daily supplement called NeuroAiD to see if it helps people recover after a mild or moderate stroke. It looks at how well patients feel and function in their daily life during recovery.
This study looks at how certain proteins in the blood change after a procedure to remove a large blockage in a brain artery. The goal is to better understand recovery after stroke treatment.
Hear when a new Stroke trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.