Treating shock in young children with severe malnutrition and diarrhea
Part of Hormones & metabolism, Infections clinical trials.
This study tests a treatment approach to help children who are in “shock” (their body is struggling to maintain blood flow and oxygen) caused by diarrhea and severe undernutrition. It may help care teams stabilize children faster and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is 1 to 59 months old and has diarrhea and acute malnutrition
- Your child has fluid-refractory shock (shock that is not improving with fluids alone)
- Your child has one of these conditions: cerebral palsy and/or developmental delay, or Down syndrome (with or without heart problems)
- A parent or caregiver can provide consent for the study
- Your child should not need breathing resuscitation (like CPR) during screening, and should not be gasping for air
- Your child’s blood should not be a rare blood type that is hard to match (if a matching donor is not available)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 study tests whether starting a blood-pressure medicine earlier in the emergency room can improve outcomes for people with low blood pressure or shock. It focuses on patients who have already received enough IV fluids and meet specific blood pressure and lab findings.
This trial tests if methylene blue given through an IV can help newborns with severe septic shock that isn't getting better with standard treatments like fluids and blood pressure medicines.
This study compares two medicines, adrenaline and dopamine, to see which works better for children with septic shock (a serious infection causing very low blood pressure) that does not improve with fluids.
This study tests whether giving a medicine to support blood pressure (inotrope) early, along with extra fluids, can help children with sepsis and shock. It may be an option for children whose shock is not improving after initial fluids.
This trial studies whether “blood pressure–supporting” medicines (given through a central line) work well and safely for adults in the ICU who have shock. Your team may use the results to improve care for people with low blood pressure and poor blood flow to organs.
This study looks at how well the heart and blood vessels are working in children with shock in the pediatric intensive care unit. The goal is to find better ways to monitor and treat them.
Hear when a new Blood Transfusion trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.