Adrenaline vs. Dopamine for septic shock in children
Treatments studied
Part of Infections clinical trials.
This study compares two medicines, adrenaline and dopamine, to see which works better for children with septic shock (a serious infection causing very low blood pressure) that does not improve with fluids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Ages 1 month to 12 years old
- Diagnosed with septic shock that hasn't gotten better with fluids
- No heart-lung bypass surgery in the last 5 days
- No long-term conditions like chronic kidney disease, cerebral palsy, congenital heart disease
- No neuromuscular or metabolic disorders
- Not treated elsewhere for low blood volume without clear medication records or showing signs of organ failure
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests different combinations of blood pressure medicines given to patients on a breathing machine who have septic shock. The goal is to find the best dose of a second medicine when norepinephrine alone isn't enough.
This trial examines how the renin-angiotensin-aldosterone system (a hormone system that helps control blood pressure) changes in patients with septic shock, compared to those with sepsis without shock, cardiogenic shock, and healthy volunteers. The goal is to better understand these changes and possibly improve treatment.
This trial tests whether different blood pressure medicines protect kidney function better in people with septic shock (a severe infection that causes low blood pressure). It compares norepinephrine (the standard treatment) with other options to see which is best for the kidneys.
This trial tests whether giving a medicine called norepinephrine early and adjusting the dose quickly can help people with sepsis who have very low blood pressure. It is for adults who are diagnosed within the last 3 hours and who have not already received this medicine.
This trial tests whether adding vasopressin (a drug that helps raise blood pressure) to standard treatment can help people with septic shock. It is for adults who already need a high dose of another blood pressure medicine called noradrenaline.
This study tests two blood pressure-raising medicines, norepinephrine and angiotensin-II, in people with septic shock. It aims to see which one works better to improve blood flow and oxygen delivery to organs.
Hear when a new Septic Shock trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.