Early blood-pressure support in the emergency department
Treatments studied
Part of Heart & circulation, Infections clinical trials.
This Phase 3 study tests whether starting a blood-pressure medicine earlier in the emergency room can improve outcomes for people with low blood pressure or shock. It focuses on patients who have already received enough IV fluids and meet specific blood pressure and lab findings.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old.
- You are in the emergency department with low blood pressure or shock, such as low systolic blood pressure or low mean blood pressure plus higher lactate (a blood marker).
- You received at least 500 mL of IV fluids (including fluids given before reaching the hospital) within 4 hours of arriving in the ER.
- Your frailty score is usually 4 or less, or an ICU doctor agrees you can be admitted even if the score is 5+.
- Your treating team does not think your shock is from heart failure, severe allergy, major bleeding, or a nerve problem.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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