Clin2
NCT04769206Possibly a fitRecruiting

Boost nerve signaling to improve blood vessel function

Endothelial Dysfunction

Part of Heart & circulation clinical trials.

This study tests a treatment aimed at increasing “rest-and-digest” nerve activity to improve how blood vessels work, especially in people with vascular oxidative stress. It is designed for African American adults and looks at whether the intervention can improve blood vessel-related health markers.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
160 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You are African American
  • You are between 18 and 60 years old
  • Your body mass index (BMI) is above 28
  • You do not have a history of heart attack, angina, heart failure, stroke/TIA, or major heart/vascular procedures
  • Your blood pressure is controlled (not staying above 140/90) even with medication

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07073352Recruiting
Childhood stress and blood vessel aging in young adults

This study looks at how childhood stress might affect blood vessels and aging in young adults. It tests if a certain protein (SIRT1) is linked to early blood vessel aging.

Iowa City, Iowa
NCT05388032Recruiting
Test whether lowering salt improves blood vessel health

This trial studies whether a lower-salt plan can improve how your blood vessels work. It’s meant for adults with higher blood pressure who may be at risk for heart and blood vessel problems.

New Orleans, Louisiana
NCT06825143Not yet recruiting· Early Phase 1
Reducing heart and blood vessel injury after blood flow changes

This trial tests if certain strategies can reduce damage to blood vessels when blood flow is restored after being blocked. It seeks sedentary adults who have not exercised regularly and are not on heart medications.

Gunnison, Colorado
NCT05483465Recruiting· Phase 4
NAD supplement trial for brain blood vessel health in aging

This trial studies whether taking an NAD supplement can support brain blood vessel health as people age. Participants will be tested for brain and health changes and may help researchers understand how to keep the brain’s blood vessels healthier over time.

Oklahoma City, Oklahoma
NCT06345443Enrolling by invitation
Nicotinamide riboside for blood vessel health

This trial tests a nutritional supplement (nicotinamide riboside) to see how it affects blood flow in healthy adults. It may help understand how to support vascular health as we age.

Rochester, Minnesota
NCT04832009Recruiting· Early Phase 1
Test a way to improve blood vessel function with lifestyle

This early-phase study looks at whether a treatment can help reverse problems in blood vessels caused by high glucose (sugar) and blood fat signals. It may be a fit if you are generally healthy, have normal insulin and sugar levels, and have a stable weight.

Kansas City, Kansas

Hear when a new Endothelial Dysfunction trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.