MR-guided radiation plus nanoparticles for central lung or pancreatic tumors
Part of Cancer, Lungs & breathing clinical trials.
This early-phase study tests a new way to deliver focused radiation using MRI guidance and tiny particles, aiming to treat certain central lung tumors or locally advanced pancreatic cancer. It’s designed to see how safe it is and how well it can control these tumors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed non-small cell lung cancer (NSCLC) in a central area, or pancreatic ductal adenocarcinoma in the pancreas
- Your cancer can be measured on scans (a visible spot at least 20 mm on standard imaging, or 10 mm on specific CT/MRI methods)
- If you have lung cancer: it must be unresectable or you can’t have surgery, and there must be no lymph node spread (N0); tumor size must be 5 cm or less
- If you have pancreatic cancer: it must be locally advanced/unresectable (near major blood vessels) and you must have finished at least 3 months of standard chemotherapy with no more than a 10-week break before this study
- No distant spread (no metastases), and you must be at least 18 with good enough blood counts and organ function
- You must be able to follow breathing instructions for the MRI-guided treatment, and you must be willing to use birth control during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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