Hormone therapy study on eating, energy, and heart health
Part of Heart & circulation, Hormones & metabolism clinical trials.
This study looks at how cross-sex hormone therapy affects appetite (eating behavior), metabolism (how your body uses food), energy balance, and cardiovascular (heart and blood vessel) health. You may be included if you meet specific health and safety requirements and can follow study procedures.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a transgender person currently receiving cross-sex hormone therapy (not just planning to start).
- You can give informed consent yourself; if under 18, all legal guardians must consent.
- For part B: your weight has stayed about the same (within 5%) for the last 3 months.
- For part B: your body mass index (BMI) is 30 or less.
- You do not have serious or uncontrolled health problems (like uncontrolled blood pressure, severe heart failure, recent stroke, or active cancer).
- If joining part D: you can safely have an MRI scan (no metal/tattoos in the head/neck area and you can tolerate being in a scanner).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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