Clin2
NCT04869436Possibly a fitRecruiting

Dupilumab to improve smell in nasal polyps

Chronic Rhinosinusitis With Nasal PolypsOlfactory Disorder

Treatments studied

Part of Ear, nose & throat, Immune system & allergy clinical trials.

This trial studies whether dupilumab can improve smell in adults whose nasal polyps are causing long-lasting smell loss. It may help learn how well the treatment restores smell, so future patients can benefit sooner.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
27 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older
  • You have chronic sinus inflammation with nasal polyps
  • You have loss of smell (olfactory loss)
  • Your doctor says dupilumab is an appropriate treatment for you
  • Your smell loss is due to nasal polyps, not another cause

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06398873Recruiting
Dupilumab and nasal lining in chronic sinusitis with polyps

This study tests whether dupilumab, a medication given as an injection, helps improve the lining of the nose in people with chronic sinus inflammation and nasal polyps. If you have nasal polyps and are about to start dupilumab, or if you have sinusitis without polyps, you may be eligible to join.

Vienna, Austria
NCT05246267Recruiting
Dupilumab study for chronic sinus disease with nasal polyps

This study looks at how dupilumab (an injection medicine) helps people with chronic rhinosinusitis with nasal polyps, including how well it works across different ethnic backgrounds. You may be able to join if you’ve been diagnosed and you can get dupilumab through insurance or a patient assistance program.

The Bronx, New York
NCT06556264Not yet recruiting· Phase 4
Dupilumab's immune effects in asthma and nasal polyps surgery

This study is testing if a drug called Dupilumab affects your immune system when you have both asthma and nasal polyps and are having sinus surgery. It might help doctors understand how to better treat these conditions together.

NCT07187583Recruiting· Phase 4
Reducing biologic doses for chronic sinusitis with polyps

This trial tests if patients with chronic sinusitis and nasal polyps can safely reduce how often they take their biologic medication (dupilumab or mepolizumab) after their disease has been partly controlled for at least a year.

Aalborg
NCT06892704Recruiting
Dupilumab smell restoration study for CRSwNP

This study tests if the medication dupilumab can improve smell loss in people with chronic sinusitis and nasal polyps. Researchers will check if blocking in the nose and electrical signals in the brain can predict who will benefit.

Chicago, Illinois
NCT05094570Recruiting· Phase 4
Dupilumab for nasal polyps with staph bacteria

This trial studies whether dupilumab (an injection) can reduce staph bacteria in the nose and make the nose’s microbes more diverse in adults with chronic rhinosinusitis with nasal polyps (CRSwNP). If you already have a plan to start dupilumab as standard care, the study may help doctors better understand why it works.

Charlottesville, Virginia

Hear when a new Chronic Rhinosinusitis With Nasal Polyps trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.