Re-irradiation plus heat for tumors that came back locally
Part of Cancer, Digestive system, Hormones & metabolism, Injuries & trauma, Kidney & urinary, Women’s health & pregnancy clinical trials.
This Phase 2 study tests using heat (hyperthermia) together with a second course of radiation to treat tumors that have returned in a limited area. It may help improve tumor control when tumors can’t be treated with surgery, but are in a body area where heat can work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your cancer has come back (local, regional, or a few limited spots—up to 3 lesions).
- You’ve already had radiation to the same side, with a dose above 30 gray-equivalent (EQD2).
- At least one of the tumor spots can be treated with heat, and that area is in the abdomen, pelvis, arms/legs, spine, or certain neck lymph nodes.
- The plan includes a second radiation course of at least 40 gray-equivalent (EQD2).
- You have 3 or fewer visible tumor lesions to treat (more than 3 means you likely can’t join).
- You don’t have certain exclusions like brain metastases or a treatment location where heat can’t be applied (like lung, liver, or mediastinum).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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