Heat therapy plus second radiation for cancer that came back
Part of Cancer, Digestive system, Hormones & metabolism, Injuries & trauma, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests whether adding heat therapy (hyperthermia) to a second round of radiation can help treat cancer that has come back in the same area after previous radiation. It may be an option if your tumor is in a part of the body that can be safely heated, like the belly or limbs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have already had radiation therapy to the same area, with a total dose higher than 30 Gray (a standard unit of radiation).
- Your cancer has come back in that area, or you have up to 3 tumors, with at least one in a previously radiated spot. Tumors can be local, regional, or in a few other places (oligometastatic).
- The tumor is in a location that can be heated, such as the belly, pelvis, arms, legs, spine, or neck lymph nodes (not in the lungs, liver, or middle of the chest).
- You are able to receive at least 40 Gray of radiation again (calculated in a special way, EQD2).
- You do not have more than 3 macroscopic (visible) tumor lesions, and no cancer in the brain.
- You do not have serious heart disease, a pacemaker/defibrillator, or large implants in the area to be treated, and you are generally healthy enough to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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