Inhaled magnesium and sildenafil for newborn lung blood pressure
Treatments studied
Part of Genetic & congenital, Lungs & breathing clinical trials.
This study tests whether breathing in magnesium sulfate and giving sildenafil can improve breathing and lung blood vessel pressure in newborns with persistent pulmonary hypertension. It may help newborns who are having trouble oxygenating despite being on a ventilator.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born at 36 weeks or later
- Your baby’s birth weight was 2.5 to 4 kg
- Your baby is between 6 and 72 hours old when the treatment starts
- An ultrasound of the heart (echocardiogram) confirms persistent lung blood pressure problems
- Your baby needs a breathing machine (mechanical ventilation) and has high oxygen needs (OI > 30 on two checks)
- Your baby can start treatment after consent is obtained
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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