Nitric oxide treatment for newborns with breathing failure and high blood pressure in the lungs
Part of Genetic & congenital, Lungs & breathing clinical trials.
This trial tests a portable device that delivers nitric oxide gas to help newborns with severe breathing problems and high blood pressure in the lungs. It aims to see if this treatment improves oxygen levels and supports recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby must be at least 34 weeks along at birth and 30 days old or younger when treatment starts.
- Your baby must have high blood pressure in the lungs, confirmed by an ultrasound of the heart.
- Your baby must need a breathing machine (ventilator) due to severe breathing failure.
- Despite the breathing machine, your baby's oxygen levels are still low (oxygen index of 20 or more, or needing high oxygen concentration).
- You must be part of the French social security system and give written permission (consent) for your baby to join.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether inhaled nitric oxide gas can help full-term newborns who have severe breathing problems and high blood pressure in their lungs. It aims to improve oxygen levels and reduce the need for more intensive support.
This trial tests a new, smart way to slowly reduce (wean) the inhaled nitric oxide gas that helps babies with a serious lung condition called PPHN. If your baby is already responding well to iNO and needs it for at least 24 hours, this study might help make the weaning process safer and more effective.
This study looks at whether an inhaled nitric oxide generator and delivery system can help newborns with high lung blood pressure (pulmonary hypertension). It may help improve oxygen levels during breathing support, but it requires specific medical eligibility and informed consent.
This trial tests whether giving a gas called inhaled nitric oxide helps newborns with a congenital diaphragmatic hernia breathe better and improve lung blood pressure. It's a type of treatment often used to help with lung problems in babies.
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
This trial tests whether inhaled nitric oxide can help people with severe obesity who are on a breathing machine because their lungs aren't getting enough oxygen. It aims to see if this treatment improves oxygen levels and recovery.
Hear when a new Hypoxic Respiratory Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.