Blood-cleaning treatment after first heart attack
Part of Heart & circulation clinical trials.
This trial tests whether a blood-cleaning procedure called CRP apheresis, given after a first heart attack, can improve recovery when a heart-attack blood marker (CRP) is high. It’s aimed at people whose heart attack is treated quickly with a procedure to open blocked arteries, and who are well enough for heart MRI scans.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had your first acute STEMI heart attack, diagnosed by heart ECG findings
- Your symptoms started more than 30 minutes ago but less than 12 hours before the artery-opening procedure
- Your CRP blood test is high (at least 7 mg/L) between 6 and 16 hours after the artery-opening procedure
- You are eligible for the primary PCI procedure (the standard emergency artery-opening treatment)
- You can have a heart MRI scan (CMR) and you are not in severe shock or needing major resuscitation
- You are 18 or older and can give written consent (not pregnant)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether adding a special heart “reset” step (ischemic postconditioning) and using an imaging guide during the emergency procedure can improve outcomes for people having a STEMI heart attack. It’s meant to optimize treatment when a blocked heart artery is being opened.
This study looks at arteries in the heart that aren't the one that caused the heart attack. It uses a special CT scan to understand these arteries better in people who have already had a procedure to open the blocked artery.
This trial tests a treatment called CRP apheresis, which filters a protein that causes inflammation from your blood during a heart attack complicated by cardiogenic shock. The goal is to reduce inflammation and improve recovery in people undergoing a heart procedure to open blocked arteries.
This trial tests whether giving a strong cholesterol-lowering treatment within 24 hours of a heart attack (during the procedure to open blocked arteries, called PCI) can reduce the risk of further heart problems. It aims to see if a rapid drop in cholesterol helps patients recover better.
This study looks at blood tests and heart function after a first heart attack (STEMI) treated with emergency stenting. Researchers want to see if certain molecules in the blood can predict future heart problems.
This study uses advanced heart scans (MRI) before and after a common artery-opening procedure to see how the heart heals. It only includes people having their first heart attack who get emergency treatment with a stent.
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